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- DOI 10.18231/j.jds.2022.009
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Apexification of an infected untreated immature tooth with calplus (Calcium hydroxide paste with Iodoform)
Introduction
Apexification is a method to induce a calcific barrier across an open apex of an immature, pulpless tooth.[1], [2] It is the process in which an environment is created within the root canal and periapical tissues after death of pulp, which allows a calcified barrier formation to occur on an open apex.[3], [4] An open apex due to the absence of sufficient root development to provide a conical taper to the canal is called Blunder Buss canal.[1], [5] Apexogenesis can also be defined as the treatment of a vital pulp by pulp capping or pulpotomy in order to permit continued physiological closure of open apex and growth of root.[6] Although opposite has been reported by Chala et al.[7] duration of this method has several drawbacks such as the risk of tooth fracture due to prolonged use of CaOH2 [8] with re-infection of the root canal[9] or difficulties in patient recall. Considering all these negative factors, single-visit apexification is suggested for the management of teeth with open apex.[10] Mineral trioxide aggregate (MTA) was first introduced in 1993 by Torabinejad et al [11] and received food and drug administration approval in dentin formation occured around large particles in contrast to small particles. It was described as an alternative to traditional apexification treatment [12] which incorporates the application of the material in the apical third of the canal to create an apical barrier. MTA is a biomaterial with excellent biocompability and superior sealing abilities even in the presence of moisture. Kaiser in 1964 first introduced Calcium Hydroxide in apexification mixed with CMCP which was later popularized by frank, Klein & Levy 1974 [5] used Calcium Hydroxide and Cresatin. Other materials used are MT A, Biphasic calcium phosphate, Hydroxyapatite and dentin chips. Nevins (1978) suggested use of collagen-calcium phosphate gel.
Apexogenesis (root formation)
Apexogenesis describes the continued physiologic development and formation of the root’s apex in vital young permanent teeth. It can be achieved by implementing the appropriate vital pulp therapy techniques. [13], [14]
Apexification (root end closure)
Apexification is a technique of inducing root end closure in an immature nonvital permanent tooth by removing the coronal and radicular tissue and placing a suitable biocompatible agent. [15], [16]
Case Report
An 8 year-old boy had reported to Dr. Shakir’S Dentzmania Dental Care with the chief complaint of pain and swelling in the maxillary anterior region for the past 1 week. He had suffered dental trauma 5 years back. On Intraoral examination Ellis class II fracture in maxillary left central incisor. Coronal access was prepared with a round burr and the canal was easily located. Working Length was determined through radiography. Gentle circumferential filing used to remove necrosed pulp. Copious irrigation with 2.5% NaOCl was done along with continuous aspiration. The canal was dried with sterile paper points and a mixture of CaOH2 with Iodoform was placed inside.

Conflict of Interest
The authors declare that there is no conflict of interest.
Source of Funding
None.
References
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How to Cite This Article
Vancouver
Rather SH, Sidat SS, Mir H. Apexification of an infected untreated immature tooth with calplus (Calcium hydroxide paste with Iodoform) [Internet]. J Dent Spec. 2025 [cited 2025 Sep 09];10(1):36-37. Available from: https://doi.org/10.18231/j.jds.2022.009
APA
Rather, S. H., Sidat, S. S., Mir, H. (2025). Apexification of an infected untreated immature tooth with calplus (Calcium hydroxide paste with Iodoform). J Dent Spec, 10(1), 36-37. https://doi.org/10.18231/j.jds.2022.009
MLA
Rather, Shakir Hussain, Sidat, Sohel Salim, Mir, Humaira. "Apexification of an infected untreated immature tooth with calplus (Calcium hydroxide paste with Iodoform)." J Dent Spec, vol. 10, no. 1, 2025, pp. 36-37. https://doi.org/10.18231/j.jds.2022.009
Chicago
Rather, S. H., Sidat, S. S., Mir, H.. "Apexification of an infected untreated immature tooth with calplus (Calcium hydroxide paste with Iodoform)." J Dent Spec 10, no. 1 (2025): 36-37. https://doi.org/10.18231/j.jds.2022.009