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- DOI 10.18231/j.jds.12168.1858687868
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The effect of vibratory stimulus oninterleukin 1ß levels and its correlation with the rate of tooth movement during retraction- A split mouth study
Aim and Objectives: Prolonged orthodontic treatment duration is a major concern in clinical practice. Techniques aimed at accelerating tooth movement include both biochemical and physical stimulation methods. This study evaluated the effect of vibratory stimulus on Interleukin-1β (IL-1β) levels in gingival crevicular fluid (GCF) and its correlation with the rate of canine retraction.
Materials and Methods: A split-mouth clinical study was conducted on 10 patients undergoing maxillary first premolar extractions. Canine retraction was performed using NiTi coil springs on both sides; one side received additional vibratory stimulus via electric toothbrush use (8 minutes twice daily for 8 weeks). GCF samples were collected at 0 (T0), 24 hours (T1), 4 weeks (T2), and 8 weeks (T3). IL-1β levels were analyzed using ELISA. Tooth movement was measured using digital calipers, and pain perception was assessed using a visual analog scale (VAS). Statistical analysis was conducted using Wilcoxon signed-rank test, paired t-test, and Pearson’s correlation.
Results: Both groups showed a significant increase in IL-1β levels at 24 hours, followed by a gradual decline toward baseline by 8 weeks. There was no statistically significant difference in the rate of tooth movement or IL-1β levels between the vibratory and control groups. However, patients in the vibratory group reported significantly lower VAS pain scores.
Conclusion: Vibratory stimulus does not enhance the rate of tooth movement or sustain elevated IL-1β levels but is effective in reducing orthodontic pain. No correlation was found between IL-1β levels and rate of tooth movement.
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How to Cite This Article
Vancouver
Kumar P, Agrawal S, Sharma P, Jain S, Shetty D, Singh B. The effect of vibratory stimulus oninterleukin 1ß levels and its correlation with the rate of tooth movement during retraction- A split mouth study [Internet]. J Dent Spec. 2025 [cited 2025 Oct 01];13(2):254-261. Available from: https://doi.org/10.18231/j.jds.12168.1858687868
APA
Kumar, P., Agrawal, S., Sharma, P., Jain, S., Shetty, D., Singh, B. (2025). The effect of vibratory stimulus oninterleukin 1ß levels and its correlation with the rate of tooth movement during retraction- A split mouth study. J Dent Spec, 13(2), 254-261. https://doi.org/10.18231/j.jds.12168.1858687868
MLA
Kumar, Piush, Agrawal, Shreya, Sharma, Payal, Jain, Shubhangi, Shetty, Divya, Singh, Bhupender. "The effect of vibratory stimulus oninterleukin 1ß levels and its correlation with the rate of tooth movement during retraction- A split mouth study." J Dent Spec, vol. 13, no. 2, 2025, pp. 254-261. https://doi.org/10.18231/j.jds.12168.1858687868
Chicago
Kumar, P., Agrawal, S., Sharma, P., Jain, S., Shetty, D., Singh, B.. "The effect of vibratory stimulus oninterleukin 1ß levels and its correlation with the rate of tooth movement during retraction- A split mouth study." J Dent Spec 13, no. 2 (2025): 254-261. https://doi.org/10.18231/j.jds.12168.1858687868